Content
Instructions for the use of "Nosematsid", attached to the drug, will help determine the timing of the treatment of insects from invasive infection. It indicates in what dosage to use the agent to treat or prevent infection. As well as the shelf life and composition of the drug.
What is the danger of infection
Causative agent nosematosis is a microscopic intracellular microsporidium Nosema apis (nosema), which parasitizes in the rectum of insects, affects the submandibular glands, ovaries, hemolymph.
The microorganism at the cellular level forms spores covered with a nitrogen-containing polysaccharide (chitin), thanks to the peculiarity of its protection, it maintains a long-term viability outside the insect's body. Together with feces, it falls on the walls of the hive, honeycomb, honey. During the cleaning of the cells, when using bee bread or honey, the spores enter the bee's body, transform into a nozema, and affect the intestinal walls.
Signs of illness:
- loose insect stool on frames, hive walls;
- bees are sluggish, incapacitated;
- enlargement of the abdomen, vibration of the wings;
- falling out of the taphole.
The bee flow rate decreases, and many bees do not return to the hive. The uterus stops laying eggs. The babies are not fully fed due to the disease of the bees responsible for this function. The swarm weakens, without treatment the bees die. The infected family poses a threat to the entire apiary, the infection spreads quickly. The honey bribe is reduced by half, the spring dry season can be 70% of the swarm. The surviving insects are infected and cannot be used to strengthen another family.
New generation drug for bees "Nosemacid"
"Nosemacid" is the latest generation of invasive, antibacterial agents. It is used for the prevention and treatment of nosematosis in bees and other infections.
"Nosemacid": composition, form of release
The main active ingredient in the composition is furazolidone, belongs to the group of nitrofurans, has an antimicrobial effect. Auxiliary components of Nosemacid:
- nystatin;
- oxytetracycline;
- metronidazole;
- vitamin C;
- glucose.
The antibiotics that are part of the drug stop the growth of colonies of pathogenic fungi, which include Nosema apis.
The pharmaceutical industry produces the product in the form of a dark yellow powder. The medicine is packaged in polymer bottles weighing 10 g. The amount of "Nosemacid" is calculated for 40 applications. Used for treatment in large apiaries with massive infestation of bees. Smaller volume - 5 g, packed in a foil bag for 20 doses. It is used for single foci or to prevent the spread of infection to other families.
Pharmacological properties
The drug "Nosemacid" with a wide spectrum of action. Furazolidone in the composition disrupts the respiration of microsporidia at the cellular level. It provokes the inhibition of nucleic acids, in the process the protective membrane of the microorganism is damaged, it releases a minimum concentration of toxins. The growth of pathogenic microflora in the insect's rectum stops.
Antibiotics (oxytetracycline, nystatin, metronidazole) have antifungal and antibacterial effects.They destroy the cellular membrane of the parasitic fungus, which leads to its death.
"Nosemacid": instructions for use
The instructions for use of "Nosemacid" include a complete description of the innovative drug:
- composition;
- pharmachologic effect;
- form of release, volume of packaging;
- the term of possible use from the date of production;
- required dosage.
As well as recommendations for use, the optimal time of the year for effective treatment and prevention of nosematosis. Special instructions for the use of "Nosemacid".
Dosage, application rules
In the spring, before the flight, the bees are given a specially prepared substance (kandy) made of honey and powdered sugar:
- 2.5 g of the drug is added to the mixture per 10 kg.
- Distribute in the hives, 500 g per family, consisting of 10 frames.
After the flight, the treatment is repeated, instead of kandy, sugar (syrup) dissolved in water is used:
- It is prepared in the same proportion - 2.5 g / 10 l.
- Top dressing is carried out twice with an interval of 5 days.
- The volume of syrup is calculated as 100 ml per bees from one frame.
Features of the use of "Nosemacid" in the fall
Infection in the summer is not accompanied by any symptoms, only after a certain time the fungus infects the bees. The disease progresses during the winter. It is recommended to carry out prophylaxis with "Nosemacid" of the entire apiary in autumn. The drug is added to the syrup at the same dosage as in the spring. One feeding is enough.
Side effects, contraindications, restrictions on use
The drug has been fully tested, no contraindications have been established. If you follow the instructions for use of "Nosemacid" for bees, there are no side effects. It is not recommended to treat infected insects during pumping out of the bee product and 25 days before the main honey harvest. Honey obtained from a sick family can still be consumed, since Nosema apis does not parasitize in the human body.
Storage rules for the drug
After opening, "Nosemacid" is stored in its original packaging. At temperatures below zero, the drug loses its healing properties, the optimal thermal regime is from 0 to 270 C. The place should be away from food and animal feed. Out of the reach of children, away from direct exposure to ultraviolet radiation. Shelf life is 3 years.
Conclusion
Instructions for the use of "Nosemacid" are designed for the treatment of a fungal disease that causes diarrhea in bees. An innovative, effective remedy relieves nosematosis in 2 doses. Recommended for prophylaxis in healthy individuals.
